49ers vs. Bills Preview and Prediction

49ers vs. Bills: Detailed Breakdown

Matchup Overview

• Teams: 49ers vs. Bills
• Date: Sunday, December 1, 2024
• Time: 8:20 PM ET
• Venue: Highmark Stadium
• NFL 2024 stats, rosters and injury reports

Current Betting Odds

• Spread: 49ers favored at -2
• Total (Over/Under): 47
• Moneyline Odds: 49ers -125, Bills +105

Dimers' Win Probabilities

• 49ers: 57%
• Bills: 43%

Dimers.com's predictive NFL model, renowned for its accuracy, assesses each team's chances by simulating the outcome of the game 10,000 times. This method provides a precise and unbiased view.

Projected Final Score

Our predicted final score for this NFL matchup is 49ers 24-22 Bills.

This prediction is based on each team's average score and player stats following 10,000 game simulations.

Our Prediction: Who Wins?

After extensive simulations, our model gives the 49ers a win probability of 57%, while the Bills have a win probability of 43%.

Summary

The 49ers face off against the Bills in the NFL at Highmark Stadium on Sunday, December 1, 2024. On this page, you'll find our preview, analysis and data-driven projections for the game.

Our 49ers vs. Bills predictions, based on sophisticated simulations and current data, guide you in making informed decisions. Remember to bet responsibly and within your financial limits.

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